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10.1111/acel.12013 217 YanL.VatnerD

Additionally, when aged cells excessively accumulate in the body, the release of highly reactive molecules such as reactive oxygen species and reactive nitrogen species (RNS) increases, inducing OS

This rapid clearance profile is essential for procurement in studies requiring physiological, pulsatile receptor activation rather than continuous baseline elevation, ensuring long-term assay reproducibility

Phytomedicine 132, 155903

Al KF, Craven LJ, Gibbons S, Parvathy SN, Wing AC, Graf C, et al

Furthermore, glutamate diffusion outside the synapse can lead to the loss of synaptic fidelity and specificity of neurotransmission, contributing to circuit dysfunction and behavioral pathology