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Histone deacetylase inhibitors increase glucocerebrosidase activity in Gaucher disease by modulation of molecular chaperones

This network approach was chosen to integrate complex metabolic data and highlight potential mechanistic connections, allowing us to identify functional relationships that may underlie the effects of NPs-FM19G11 treatment

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P 2.0 mg dl 1 was present in 36.4% of patients in the overweight BMI category, with a progressive increase to 43.3%, 57.3% and 72.0% for patients in the class I, II and III obesity categories, respectively