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Lipid nanoparticles-from liposomes to mRNA vaccine delivery, a landscape of research diversity and advancement

doi: 10.1038/s41418-019-0380-z 26 UrsiniFMaiorinoMGregolinC

Importantly, these effects could be recapitulated in cysteine desulfurase (NFS1) knockdown cells with impaired iron-sulfur cluster synthesis, indicating that phenotypes observed in SLC25A39/40 knockout cells are likely a consequence of an iron-sulfur cluster deficiency (Extended Data Fig