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The loss of GSH disrupts redox homeostasis, leading to ROS accumulation and, subsequently, cellular dysfunction and death [10]

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For labelling metabolomics experiment, epSPCs were cultured for 48 h in the proliferative medium supplemented with 3 g/L of [U- 13 C 6 ] glucose (Cambridge Isotope Laboratories, Tewksbury, MA, USA)

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As a result, mitochondria have significance to the ferroptosis process

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