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The MRN complex, consisting of MRE11, RAD50, and NBS1, plays a critical role in detecting and signaling DSBs ( Figure 2 Relative resistance to radiation-induced damage in the S phase is thought to be due in part to an elevated amount of DNA synthesis and repair enzymes, as well as increased intracellular levels of glutathione (a free radical scavenger) ( Historical perspectives on genetic associations with radiosensitivity In war, the victorious strategist only seeks battle after the victory has been won, whereas he who is destined to defeat first fights and afterwards looks for victory. - The Art of War , Sun Tzu A rational starting point to identify potential somatic molecular alterations in cancer cells which might be associated with increased radiosensitivity is to review early key observations linking individual genetic mutations to syndromes characterized by heightened radiation toxicity

It also helps deliver energy needed for workouts by enhancing mitochondrial energy production and supporting fat metabolism

La supplmentation en glutathion est couramment recommande aux personnes qui suivent un entranement intense, celles qui souffrent de maladies chroniques et pour soutenir le systme immunitaire

Am J Surg 168(6):576-9

Ohnishi, K

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