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It has since been characterised as a far broader regulatory glycoprotein, functioning as a high-affinity binding protein for multiple members of the TGF- superfamily most notably myostatin and activin A, but also bone morphogenetic proteins (BMPs) including BMP-2, BMP-5, BMP-7, and BMP-8

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Yokoyama MT, Carlson JR

[DOI] [PubMed] [Google Scholar] [103].Bernfeld P, Wan J, Antigens and enzymes made insoluble by entrapping them into lattices of synthetic polymers, Science 142 (1963) 678679

Two days post transfection, IgM-negative Ramos B cells were transduced with HEK293T supernatant