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For example, SHPRH-146aa limits the PCNA protein level and thereby glioblastoma cell proliferation by protecting full-length SHPRH, which is the ubiquitin ligase E3 of PCNA (Zhang et al, 2018a)

The gut microbiome in atherosclerotic cardiovascular disease

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For example, some men simply have a testosterone imbalance and require another, more comprehensive treatment, like hormone replacement therapy