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Resveratrol (3,3,3-triydroxy-trans-stilbene), a phenol derived from the root of knotweed (Polygonium cuspidatum), found in Japan and China [335]

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Methods: A 61-year-old man was diagnosed with chronic hepatitis C in April 2000 and treated by conventional interferon (IFN) monotherapy for 24 weeks from August 2000 to January 2001

These findings and the observation that AnPrx6 contains a sequence motif highly conserved in Prx6 proteins not found in other Prx families, raised the questions: ( i ) does AnPrx6 possess unique functional attributes, and ( ii ) can the high-resolution crystal structure provide a molecular level understanding of the function of AnPrx6 and perhaps of Prx6 proteins in general

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Along these lines, LC3B-II / LC3B-I ratios, assessed by western blot, were increased in differentiated GDAP1-null cells relative to wild-type controls (Fig