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At the same time, they strongly inhibit active oxygen and scavenge free radicals, and can reduce lipid peroxidation caused by iron overload, which results in cell damage

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At the molecular level, it seems that the mechanisms of action vary depending on the dose of metformin used and duration of treatment

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The glutaredoxin (Grx)/GSH/GSH reductase (Gor) system catalyzes specific de-glutathionylation of S -glutathionylated proteins (Fernandes and Holmgren, 2004

Brain lipid extraction and preparation of large unilamellar vesicles (LUVs) LM or PM-enriched fractions obtained from WT newborn (P1) mice (approximately 100 mg protein in NB buffer) were mixed with 25 ml of a 2:1 chloroform:methanol solution at room temperature