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298 Notably, mitochondrial copper can directly bind to proteins following their lipoylation, a post-translational modification involving the covalent attachment of an eight-carbon organosulfur lipoic acid moiety to specific lysine residues, leading to the aggregation of lipoylated proteins

PMID: 36014491 Tymoshenko, M

Oxford: Oxford University Press (2007)

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In the investigator-initiated trial, two drug-related adverse events occurred in the experimental groupspecifically, toothache and injection site swellingwhile one participant in the control group experienced an injection-related adverse event (injection site swelling)

No statistically significant changes were observed in GSH or GSSG levels, but the ratio GSH/GSSG showed a tendency to be decreased in undSOD1 and mutSOD1 from C1 and C3, compared to the respective controls