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NRF2 also induces the expression of multidrug resistance proteins, superoxide dismutase, and heme oxygenase 1

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In the early stages of DKD, the majority of patients experience an insidious onset and few overt clinical symptoms and indicators, but they are prone to develop end-stage renal disease in the later stage, which is life-threatening

In the Y-maze barrier task, prenatal stress and THC reduced high-reward arm selection at low effort (10 cm) in males, whereas females showed reduced selection primarily after prenatal exposures to THC or THC/Stress

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