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In OA, factors such as obesity and aging disrupt the integrity of the cartilage epigenome

Activated Stat5 trafficking via endothelial cell-derived extracellular vesicles controls IL-3 pro-angiogenic paracrine action

DCs activated in this manner exhibit increased glycolysis and reduced mitochondrial respiration, as well as increased Hif1a transcription

Meanwhile, the highest glutathione content and productivity were observed at a CSL concentration of 5%, showing increases of 30% and 180%, respectively, compared to YCK50D (Fig