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Without proper testing, you risk side effects such as water retention, elevated blood sugar, or suppressed pituitary function

Nrf2 is involved in not only the regulation of GSH synthesis and reduction via upgrading some enzymes and proteins (SLC7A11, GCLM, GCLC, GR) but also the activation of GSH-dependent antioxidant enzymes (GPX, GST) [200, 201]

Researchers use these systems to measure growth hormone release, receptor activation kinetics, IGF-1 expression, and downstream metabolic pathway activity