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Graphical Abstract Similar content being viewed by others Introduction Autism spectrum disorder (ASD) is a pervasive neurodevelopmental disorder characterized by social communication impairments and repetitive behaviors, with an estimated global prevalence of 0.72% [1]

Such fragmentation impairs substrate and protein exchange across the mitochondrial network, compromises m and reduces coupling efficiency between electron transport and ATP synthesis

Its ability to promote new blood vessel formation makes it especially promising for burns, chronic ulcers, and ischemic wounds

Almahariq, M., Mei, F

In several reported pediatric cases, ingestion of large amounts of alpha-lipoic acid (for example, 2400 mg in a toddler) led to serious reactions such as seizures, loss of consciousness, or metabolic acidosis

To evaluate OGDC activity, mitochondria were isolated and the -KG-dependent succinyl-CoA production rate in mitochondria lysate was measured using LCMS