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Alcohol induces changes in the regulatory mechanisms of the lung, both at a mechanical and immunological level

El-Boshy M, BaSalamah MA, Ahmad J, Idris S, Mahbub A, Abdelghany AH, Almaimani RA, Almasmoum H, Ghaith MM, Elzubier M, Refaat B

A Bayesian phase I/II platform design for co-developing drug combination therapies for multiple indications

Using MDS-UPDRS part III scores in the ON-condition at month 12 as primary outcome the trial found a statistically significant difference in favour of lixisenatide of 3 score points, but there was no significant difference on any of the secondary efficacy outcomes including MDS-UPDRS part II scores

Olin-Sandoval V, Yu JSL, Miller-Fleming L, Alam MT, Kamrad S, Correia-Melo C, et al

Amino acids are involved in various biochemical pathways that mediate the stress response (Fig