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For hair applications specifically, longer cycles of 12-16 weeks may be appropriate given the slow nature of hair regrowth, followed by 4-6 week breaks

doi: 10.1186/1471-2105-14-335 124 ZipfelC.OldroydG

The strategy involved searching the databases using the following Medical Subject Heading (MeSH) terms: breast cancer, invasive breast cancer, targeted therapy, cancer stages, cancer type, primary therapy, iron overload, iron chelator, deferoxamine, deferasirox, NF-B, and ROS

Starting from environmental factors like pollution, smoke, and micro dust, to strenuous exercise and improper diet, everything can contribute to its depletion.

(Left: Proportion of studies with low, or high, or unclear concerns regarding applicability