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In-vivo vaccination effect The binding of antibodies to exogenous antigens (e.g., viral proteins) or tumor-associated antigens can promote their uptake, processing, and cross-presentation by antigen-presenting cells (e.g., DCs), ultimately leading to priming of CD8 + T cell effectors and induction of memory responses [38, 39]

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Examples are moderate anemia that is well controlled, stable warfarin anticoagulation, well-managed PV or ET (with recent therapy and controlled counts), or leukemia patients in remission on oral targeted therapy