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Minihepcidin has been used in murine studies on iron absorption and iron homeostasis (Guggisberg et al., 2022

B., Fergusson, M

doi: 10.1002/adhm.202100149 72 IngoldIBerndtCSchmittSDollSPoschmannGBudayKet al

& Kalofonos, H

These findings support a role for apoE in suppressing ferroptosis in AD pathogenesis, and provide an explanation for why the low abundance of apoE is an independent risk factor for disease progression