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The Panel interpreted these data to indicate that for a particular patient, the balance between benefits and risks/burdens is uncertain or relatively equal and whether to use a particular treatment is a decision best made by the clinician who knows the patient with full consideration of the patient's prior treatment history, current quality of life, preferences and values

For instance, drugs, like proton pump inhibitors (PPIs) and H2 receptor antagonists, which are often prescribed for reflux treatment, can lessen the stomach's ability to produce acid