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Prodrug-based drug delivery vehicles Carrier prodrugs are compounds composed of active drugs and carriers that exhibit little or no activity in vitro

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doi:10.1016/j.reth.2019.08.004 26

Acta Biomater 186:354368

None of the major metabolites were associated with hepatotoxic, carcinogenic, immunotoxic, mutagenic, or cytotoxic risks, corroborating their safety for human use