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Song HY, Kim HM, Mushtaq S, Kim WS, Kim YJ, Lim ST, Byun EB (2019) Gamma-irradiated chrysin improves anticancer activity in HT-29 colon cancer cells through mitochondria related pathway

If side effects emerge (injection site reactions, unusual symptoms), reduce dosage or frequency

Endometriotic implants secrete estradiol (E2) as well as prostaglandin E2 (PGE2), agents that attract macrophages (monocyte chemotactic protein 1[MCP-1]), neurotrophic peptides (nerve growth factor [NGF]), enzymes for tissue remodeling (matrix metalloproteinases [MMPs]) and tissue inhibitors of MMPs (TIMPs), and proangiogenic substances such as vascular endothelial growth factor (VEGF) and interleukin-8 (6)

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Scopoletin and pinocembrin, when encapsulated in polymeric micelles, exhibit urate-lowering effects by inhibiting xanthine oxidase activity and promoting uric acid excretion, respectively, while significantly improving renal injury protection (Zeng et al., 2020

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