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Similarly, the Ma research team used the same strategy to prepare CFP2-C-5-FU-FA NPs, and confirmed through in vivo fluorescence imaging technology that the fluorescence signal intensity of the targeted nanoparticles in the tumor region was significantly higher than that of the non-targeted control group, and had lower cardiac toxicity (Figure 3C)

New York, NY: Springer, 2019, pp.289298

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Klinische Resultate und therapeutische Anwendungen von Salzen der N 5 ,N 10 -Methylen-5,6,7,8-tetrahydrofolsureClinical results and therapeutic applications of salts of N 5 , N 10 -methylene-5,6,7,8-tetrahydrofolic acid Als Beispiele der mglichen therapeutischen Anwendungen der beschriebenen Verbindungen liegen folgende klinische Ergebnisse vor: Patient A : Geschlecht: weiblich Alter: 19 Diagnose: osteogenes Sarkom mit Atmungs- und Schluckbeschwerden Behandlung: 5-Fluorouracil intravens verabreicht (300 - 750 mg/Woche) in Kombination mit intravens verabreichtem N 5 ,N 10 -Methylen-5,6,7,8-tetrahydrofolsure-Calciumsalz (100 mg/Woche)