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These findings establish a pivotal link between -KG availability and disulfidptosis, suggesting that AMPK may prevent disulfide stress accumulation through NADPH homeostasis, a notion that requires further investigation

IGF-1 DES (1-3) is a truncated 67 amino acid form, lacking the three N-terminal residues (Gly-Pro-Glu)

IGFBPs, mainly IGFBP1 and IGFBP3, regulate IGF-1 activity via releasing and sequestrating IGF-1) [33, 34]

e429 Wang Z, Diao J, Zhao X, Xu Z, Zhang X

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