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Ethics statement The animal study was reviewed and approved by Institutional Bioethics and Biosecurity Committee of the Instituto de Investigaciones Qumico-Biolgicas, Universidad Michoacana de San Nicols de Hidalgo

Microbes 12:1801944

These compounds exhibit diverse biological activities, including antimicrobial, antidepressant, anticancer, and other pharmacological effects (Yang Y

IGF-1 levels increased by a substantial 122% [7]

Because this detoxification pathway relies heavily on glutathione, a deficiency means that histamine remains circulating in the bloodstream for prolonged periods

nigrum extract on LPS-induced intracellular ROS accumulation In this study, we investigated the effect of the sub-cytotoxic concentration of RN on intracellular ROS accumulation induced by LPS treatment (at 1 g/mL)