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However, mild acute toxicity and suboptimal therapeutic efficacy have been observed following the administration of viral vectors, likely due to off-target transduction of liver-resident antigen-presenting cells (APCs), such as Kupffer cells and hepatic stellate cells [304, 305]

These research investments will help clarify whether OSCs can deliver on their promise as sustainable, dual-action therapeuticsor whether their use necessitates the same cycle of vigilance required for conventional antibiotics

Similar effects on the immune response have been observed in some animal studies (47, 48)

3 , e437 (2006)

Store reconstituted glow stack at 2-8C (35.6-46.4F), protected from light

67,124 EBV encodes the oncogene LMP1 and latent membrane protein 2A (LMP2A), which play important roles in gene expression and are thought to be involved in EBV-mediated tumorigenesis