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It is important to note that while this product is available for purchase without prescription, users should still familiarize themselves with proper injection techniques or seek assistance if uncomfortable with self-administration

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The liquid in the vial may not fill the entire vial and may look partially full

Semaglutide was initiated at 0.25 mg per week for the first 4 weeks via a pre-filled pen injector, escalating in a fixed-dose regimen every 4 weeks to reach the maintenance dose of 2.4 mg by week 16 (lower maintenance doses were permitted if participants were unable to tolerate 2.4 mg) (Extended Data Fig

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