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SKU: 78641470241
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Under normal conditions, NRF2 is held in check within the cell, bound to a protein called Keap1

The honest answer depends on your goal and how consistently you apply

Source: Butterfield, D

Since cysteine-modified Keap1 no longer binds to Nrf2, Nrf2 avoids degradation and activates the expression of its target genes under oxidative stress conditions [14,18]