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coli of both MetE full (aa 1759) protein and N-terminal MetE fragment (aa 1420), Rv1133c gene was amplified by PCR with the primers MetEFw-MetERv (for rMetE) and MetEFw-MetE 420 Rv (for rMetE 420 ) ( Supplementary Table S1 ), by using H37Rv genomic DNA as template, prepared by using the GenoLyse protocol (Hain Lifescience GmbH)

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