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Our goal is to catch the cycle before the follicle reaches a state of permanent inactivity

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The sensitivity of the developing brain to oxidative stress is high because it has the highest oxygen consumption, a high level of unsaturated fatty acids that are susceptible to lipid peroxidation, elevated iron levels that can catalyze and form hydroxyl free radicals, and low amounts of catalase (CAT), which increases the brains vulnerability to damage caused by oxidative stress [5]

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Macrophage p53 deficiency leads to enhanced atherosclerosis in APOE*3-Leiden transgenic mice