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This compound contains D-glucose, L-rhamnose, D-galactose, and D-mannose, and its main chain is composed of (1 4)-linked galactose and glucose residues

This reaction pulls two electrons from G6P in order to reduce the coenzyme NADP+ to NADPH

Identification of SLC7A5 as an Erastin Target in BJeH and BJeLR Cells Affinity chromatography and mass spectrometry were used to identify proteins that bound an active (lethal) erastin analog (erastin-A6) and an inactive control (erastin-B2) in lysates from oncogenic HRAS-mutant BJeLR cells and HRAS-wild-type BJeH cells (2 independent experimental replicates for each cell line) (Yagoda et al., 2007)

It impairs BBB permeability by inducing the degradation of tight junction proteins (e.g., occludin, claudin-5), thereby exacerbating neuroinflammation (Vezzani and Baram, 2007