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48,49 Supplementation with antioxidants can increase the activity of SOD and decrease oxidative stress in patients with CVDs

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c , Cell death quantification (% trypan blue + ) of glucose-deprived shCtrl and shGDH1 Huh7 cells treated with NAC (5 mM) for 72 h

The mechanism may involve metalloproteinases (MMPs)

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Reddy PH, Manczak M, Yin X, Grady MC, Mitchell A, Tonk S, Kuruva CS, Bhatti JS, Kandimalla R, Vijayan M et al (2018) Protective effects of Indian spice curcumin against amyloid- in Alzheimers disease