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The heterogeneity in the TME enables it to exhibit various tumour-promoting functions such as immune evasion, cell survival, physical barriers, etc., ultimately leading to the development of multidrug resistance in tumour cells [66]

Current evidence and implications for management

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For this reason, oral retinoids like isotretinoin are banned during pregnancy

An Exceedingly Rare Case of Antithrombin III Deficiency and Catastrophic Antiphospholipid-Like Disease

Fuzi decoction ameliorates intervertebral disc degeneration through ferroptosis modulation by suppressing nf-b pathway