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Epithalon Mechanisms of Action Enhances mitochondrial efficiency by reducing oxidative stress and facilitating efficient ATP production

Abkallo HM, Liu W, Hokama S, Ferreira PE, Nakazawa S, Maeno Y, Quang NT, Kobayashi N, Kaneko O, Huffman MA, Kawai S, Marchand RP, Carter R, Hahn BH, Culleton R

Altitude hypobaric hypoxia leading to hypoxemia triggers high-altitude sickness, although the precise mechanisms remain poorly understood

Taken together, many results of the in vitro experiments and clinical studies show that the most appropriate treatment is a combination of different inhibitors chosen based on the molecular properties of tumor cells

This family of compounds represents a new class of drugs with lead candidates that are orally active, penetrate the BBB sufficiently to reach therapeutic concentrations, and reverse memory deficits seen in animal models of dementia