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Mice that have genetic mutation typically develop hyperinsulinemia, hyperglycaemia, and hypercholesterolemia together with liver inflammation (Van Rooyen et al., 2011)

aegypti were collected from natural oviposition sites using standard dipping procedure

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hirae , the extracellular reductase CorA supplies Cu + for uptake by CopA ( ndh2 gene encoding a membrane-anchored type-2 NADH dehydrogenase (A1F92_RS04560) that reduces Cu 2+ to Cu + was also detected in the CAUH2 genome ( ndh2 gene and the copA gene were up-regulated 4- and 14-fold under H 2 O 2 stress, respectively, which indicates an increased requirement for copper ions in CAUH2 to maintain the activity of catalase and glutathione peroxidase under H 2 O 2 stress

The induction of cytotoxicity by H 2 O 2 is a widely adopted approach to explore the potential neuroprotective and antioxidant effects of natural products 39