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doi: 10.3389/fimmu.2019.01440 75 DaiHAdamopoulosIE

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When the agency places a compound in Category 2 under 503A or 503B, it has determined that there is insufficient evidence of clinical use, or that the compound presents concerns that make it inappropriate for compounding

The public is advised to be cautious of any marketed product for treating skin conditions (ie skin lightening)

doi: 10.1186/1742-4933-2-17 106

Collagen protein by itself might not be enough