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Vascular dysfunction in experimental diabetes is improved by pentaerithrityl tetranitrate but not isosorbide-5-mononitrate therapy

doi:10.1038/ncomms13873

15,16 This is due to the retrograde flow of menstrual blood into the abdomen, resulting in accumulation of ruptured erythrocytes (Sampsons theory of reflux)

10.1016/j.jtos.2017.05.003 Ocul

Folylpolyglutamate synthetase is responsible for the addition of a polyglutamate tail to folate and folate derivatives

The patients in DEFK group also showed a higher quality of life (QOL) scores, a lower depression and anxiety self-assessment scale (SDS and SAS) scores compared with the control group (mifepristone)