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Because the BDNF gene plays a central role in regulating neuronal survival, synaptic plasticity, and the formation of new neural connections, individuals with this genotype typically maintain normal neurotrophic signaling capacity within brain networks responsible for learning, memory, and emotional regulation

In the study of cagrilintide versus liraglutide, 706 patients aged 18 years and older without diabetes and with a body mass index of at least 30 kg/m 2 or at least 27 kg/m 2 with hypertension or dyslipidemia were enrolled

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