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The findings of this review can be translated into environmental monitoring and regulatory frameworks by identifying the most sensitive biomarkers of metal exposure, integrating AI-driven predictive models to detect early signs of toxicity, and informing evidence-based thresholds for water quality standards that account for sublethal and synergistic effects of metals

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This renders most glutathione supplements ineffective

Several other factors may also contribute to raised homocysteine and impaired methylation

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