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10.1016/j.cej.2023.145413 78 LiJ.CaiP.ShalviriA.HendersonJ

PharmGKB summary: very important pharmacogene information for UGT1A1

Gene editing represents a future hope, particularly for genetic forms of PD, aiming to eliminate the disease cause at its origin

Scarselli et al., 2006

And, they reverse the hypermethylation of CpG islands in the promoter region of tumor suppressor gene by upregulating genes that are methylated due to fibrosis, such as the RASAL1 gene ( However, the disadvantages of 5AC and DAC are becoming increasingly apparent