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526,527 Oxidative damage caused by inflammation can induce inflammatory reactions through the activation of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-B), a crucial transcription factor that controls the production of inflammatory cytokines such as TNF- and IL-6

A report estimated that in 2021 in the United States, there will be 1,898,160 new cancer cases and 608,570 cancer deaths (Siegel et al., 2021)

When ingested, these conjugated isoflavones undergo hydrolysis by -glycosidases in the intestine to produce bioactive aglycones (daidzein and genistein)

After gathering all available data on each patient included in the trial, the baseline values of each variable was compared using an ANOVA model including the study and treatment group

10.3390/nu14183791 80 PickichM

doi: 10.1161/CIRCRESAHA.109.215392 18 LiangSMaHYZhongZDharDLiuXXuJet al