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While effective within weeks, reductions in pulmonary vascular resistance are more pronounced after longer treatment (e.g., 6 months)

The pathological consequences of this systemic metabolic dysregulation converge on the kidney, driving the production of nephritogenic autoantibodies and fostering a local inflammatory milieu that perpetuates LN

doi: 10.3390/antiox9121285 266 ItoSNapolitanoASarnaTWakamatsuK