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The use of an optimised internal standard minimises any analytical variations that could be crucial when calculating the GSSG/GSH ratio

3.3 Mechanical stress and ECM remodeling Throughout the initiation and progression of pulmonary fibrosis, mechanical stressan essential exogenous biophysical cueis regarded as a pivotal regulator of epithelial-to-mesenchymal transition (EMT) and fibrotic tissue expansion ( Experimental data demonstrate that sustained mechanical stretch activates the TGF-/Smad axis, suppresses E-cadherin, and elevates mesenchymal markers such as Vimentin and Snail, thereby driving alveolar epithelial cells toward a mesenchymal phenotype

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The researchers measured how many of the participants neutralizing antibodies were specific for the original variant, the omicron variant or both

Oncol 36 , 19942001 (2018)

10.1038/s41569-018-0098-5 2 AhamadS.MathewS.KhanW