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Microbiome-derived lactate furthermore accelerates colonocyte turnover 121 and by activating Gpr81 either on Paneth cells or on stromal cells, augments Wnt factor-production, resulting in Lgr5 + ISCs expansion and protection from acute intestinal damage 88

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however, it can also enhance the uptake of toxic elements if mineral sufficiency is not maintained

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Electrochemical synthesis of chitosan/silver nanoparticles multilayer hydrogel coating with pH-dependent controlled release capability and antibacterial property n.d Azri FA, Selamat J, Sukor R, Yusof NA