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Studies have reported that the use of bisphosphonates can delay bone metastasis in patients with breast cancer and improve overall survival (36,37)

Immunofluorescence labeling of HSD3B in rat testes and Leydig cells Paraformaldehyde (PFA, 4%)-fixed testis sections or isolated Leydig cells (LCs) were subjected to immunofluorescence staining of 3-hydroxysteroid dehydrogenase (HSD3B)