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Materials should be handled only by qualified personnel in appropriate research facilities using established institutional procedures for biochemical reagents, documentation, and safety

A least 2 weeks prior to tissue collection, a cohort of animals were maintained in a reverse light-dark cycle in which lights were turned off at 6am and lights were turned on at 6pm

This lack of standardization introduces chaos

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TABLE 8 NWI prognostic scoring system for WD in conventional units The challenge with both the Nazer score and the NWI is interpreting scores close to the breakpoint (NWI: 1011) between need or no need for liver transplantation