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Oxidative stress*

In melanocytes 4-HNE, through adduct formation, alters protein function, contributing to oxidative stress-induced cellular dysfunction, which mainly concerns on the functioning of cellular antioxidant system, acceleration of protein degradation, inhibition of melanocyte proliferation, photoaging processes, but also disruption of the intercellular interactions between melanocytes and keratinocytes 101,102,103

Senolytics Improve AD Outcomes in Preclinical Studies Multiple independent research groups have demonstrated that D+Q clear senescent cells across biological systems (model organisms), diseases and tissues

Ferritin heavy chain protects the developing wing from reactive oxygen species and ferroptosis

Non-inflammatory pain in inflammatory arthritis

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