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Schmitt, H

Even in clinical settings, combining cetuximab with chemotherapy reduces plasma iNOS and NO levels in patients with metastatic CRC, which correlates with better T-cell responses (81)

Directly regulating these regulatory enzymes can lead to broad, unpredictable changes in gene expression and potential toxic side effects

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Although there was no significant difference between the two treatments in improving these pathological features, the overall benefit trend of caffeine was greater than that of EGCG