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We aimed to characterize the clinical significance and prognostic value of GSTA2 in HCC recipients and to investigate its functions and underlying mechanisms in HCC recurrence and metastasis

10.1002/14651858.CD009505.pub2 117 StewartE

In response to the challenges faced, multiple approaches, pathways, and strategies are under investigation e.g., senolytics and senomorphics

In addition to these indirect effects, lactate also directly modulates vascular inflammation and angiogenesis by activating nuclear factor (NF)-B and HIF-1 pathways [48,49,50,51,52]