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Comparable to these findings, the immuno-reactivities of both GPx4 and FACL4 were successfully preserved to near the normal levels under ALA treatment during CSD (Figures 2C,F)

During protein folding stress, the sirtuin SIRT7 also plays an important role by contributing to repressing nuclear respiratory factor 1 (NRF1) activity, a major transcriptional regulator of mitochondrial genes