pdb glutathione s transferase Cartoon structure of protein with pocket site (a = RCSB PDB - 1R5A: Glutathione

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This review describes the recent advancements in the application of NPTAs for AD treatment, focusing on the pathogenesis of AD, the processes by which NPTAs enter the brain, the mechanism of NPTAs in AD theranostics, and notably, the recent developments concerning various categories of NPTAs, including inorganic nanoparticles, two-dimensional nanomaterials, metal-organic frameworks, organic polymer nanoparticles, biomimetic modified nano-delivery systems, peptide-modified nano-delivery systems, and liposomes in the field of AD treatment (Fig